Protein Information

Cytoscape View


UniProt AC / UniProt ID P54869 / HMCS2_MOUSE
Protein Name Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor
Gene Name Name: Hmgcs2
Organism Mus musculus (Mouse)

PRO ID PR:P54869
DAG View
PRO Name hydroxymethylglutaryl-CoA synthase, mitochondrial (mouse)
Definition A hydroxymethylglutaryl-CoA synthase, mitochondrial that is encoded in the genome of mouse.
Short Label mHMGCS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54869 (Hmgcs2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T38 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K52 Acetylation PhosphoSitePlus
K83 Acetylation PhosphoSitePlus   UniProt 23576753
K83 Ubiquitination PhosphoSitePlus
C96 S-Nitrosylation dbSNO 20837516
C106 S-Nitrosylation dbSNO 20837516
K118 Acetylation PhosphoSitePlus   UniProt 23576753
K118 Ubiquitination PhosphoSitePlus
K137 Acetylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K243 Acetylation PhosphoSitePlus   UniProt 23576753
K243 Ubiquitination PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
K256 Acetylation UniProt 23576753
C269 S-Nitrosylation dbSNO 20837516
C305 S-Nitrosylation dbSNO 20837516, 26165157
K306 Acetylation PhosphoSitePlus   UniProt 23576753
K310 Acetylation PhosphoSitePlus   UniProt 23576753
K310 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K327 Acetylation UniProt 23576753
K327 Ubiquitination PhosphoSitePlus
K333 Acetylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K342 Acetylation PhosphoSitePlus   UniProt 23576753
K342 Ubiquitination PhosphoSitePlus
K350 Acetylation PhosphoSitePlus   UniProt 23576753
K350 Ubiquitination PhosphoSitePlus
K354 Acetylation PhosphoSitePlus   UniProt 23576753
K354 Ubiquitination PhosphoSitePlus
K358 Acetylation PhosphoSitePlus   UniProt 23576753
K358 Ubiquitination PhosphoSitePlus
K367 Acetylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K427 Acetylation PhosphoSitePlus   UniProt 23576753
K427 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus   UniProt 17208939
K437 Acetylation PhosphoSitePlus   UniProt 23576753
K437 Ubiquitination PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
K447 Acetylation PhosphoSitePlus   UniProt 23576753
K447 Ubiquitination PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus   UniProt 21183079
K473 Acetylation PhosphoSitePlus   UniProt 23576753
K473 Ubiquitination PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus