iPTMnet Report for P54829 (PTPN5)
Protein Information
| UniProt AC / UniProt ID | P54829 / PTN5_HUMAN |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 5 |
| Gene Name | Name: PTPN5 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P54829 |
| PRO Name | tyrosine-protein phosphatase non-receptor type 5 (human) |
| Definition | A tyrosine-protein phosphatase non-receptor type 5 that is encoded in the genome of human. |
| Short Label | hPTPN5 |
| Category | organism-gene |
DAG ViewP54829 (PTPN5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S245 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 21777200 | ||
| T255 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 21777200 | ||
| S268 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 21777200 | ||
| S444 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S66 | P66 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| S66 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S221 | F221 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S245 | F245 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S268 | F268 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S268 | Y268 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
