iPTMnet Report for P54802 (NAGLU)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P54802 / ANAG_HUMAN
Protein Name Alpha-N-acetylglucosaminidase precursor
Gene Name Name: NAGLU
Synonyms:UFHSD1;
Organism Homo sapiens (Human)

PRO ID PR:P54802
DAG View
PRO Name alpha-N-acetylglucosaminidase (human)
Definition An alpha-N-acetylglucosaminidase that is encoded in the genome of human.
Short Label hNAGLU
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54802 (NAGLU) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K59 Ubiquitination PhosphoSitePlus
N134 N-Glycosylation GlyGen 29391424
C136 Methylation IEDB 31844290
N261 N-Glycosylation GlyGen 23090970, 29741879, 24190977, ...29391424, 34089345
N435 N-Glycosylation GlyGen 29671580
K465 Ubiquitination PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
N503 N-Glycosylation GlyGen 23090970, 29741879, 23345538, ...24190977
N526 N-Glycosylation GlyGen 29391424, 24190977
N532 N-Glycosylation GlyGen   UniProt 19159218, 24190977
S553 Phosphorylation PhosphoSitePlus
Y583 Phosphorylation HPRD   PhosphoSitePlus 19664995
K586 Ubiquitination PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
Y715 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N435 N-Glycosylation PRO 29671580
N503 N-Glycosylation PRO 23345538


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C136 R136 Biomuta DOID:363 / uterine cancer [ icgc ]
N526 S526 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y583 H583 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y715 H715 Biomuta DOID:4159 / skin cancer [ cosmic ]