iPTMnet Report for P54756 (EPHA5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P54756 / EPHA5_HUMAN
Protein Name Ephrin type-A receptor 5 precursor
Gene Name Name: EPHA5
Synonyms:BSK,EHK1,HEK7,TYRO4;
Organism Homo sapiens (Human)

PRO ID PR:P54756
DAG View
PRO Name ephrin type-A receptor 5 (human)
Definition An ephrin type-A receptor 5 that is encoded in the genome of human.
Short Label hEPHA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54756 (EPHA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
N299 N-Glycosylation GlyGen 24190977
T301 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
N461 N-Glycosylation GlyGen 24190977
N465 N-Glycosylation GlyGen 24190977
T649 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PRO   PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus
Y656 Phosphorylation PRO   PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
T676 Phosphorylation PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus
T708 Phosphorylation PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
Y713 Phosphorylation PhosphoSitePlus
Y790 Phosphorylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
S822 Phosphorylation PhosphoSitePlus
Y833 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T835 Phosphorylation PhosphoSitePlus
T856 Phosphorylation PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
S953 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
S964 Phosphorylation PhosphoSitePlus
Y967 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y295 Phosphorylation HPRD 20068231
S960 Phosphorylation HPRD 20068231
S964 Phosphorylation HPRD 20068231
Y967 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y295 Phosphorylation HPRD 20068231
S938 Phosphorylation HPRD 20068231
S942 Phosphorylation HPRD 20068231
Y945 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047298 (hEPHA5/SigPep-/Phos:1) pY650,pY656 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 L4 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ icgc ]
T197 K197 Biomuta DOID:1324 / lung cancer [ cosmic ]
T197 I197 Biomuta DOID:1612 / breast cancer [ cosmic ]
T301 N301 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S313 L313 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T649 A649 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T649 N649 Biomuta DOID:1324 / lung cancer [ cosmic ]
T649 I649 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S673 L673 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T676 A676 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K699 N699 Biomuta DOID:1324 / lung cancer [ cosmic ]
K699 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T708 I708 Biomuta DOID:1324 / lung cancer [ cosmic ]
K710 N710 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y790 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S822 F822 Biomuta DOID:4159 / skin cancer [ cosmic ]
S822 Y822 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T856 I856 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S938 R938 Biomuta DOID:1612 / breast cancer [ cosmic ]
S938 N938 Biomuta DOID:363 / uterine cancer [ icgc ]
S942 F942 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S942 Y942 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S953 F953 Biomuta DOID:4159 / skin cancer [ cosmic ]
S960 R960 Biomuta DOID:1612 / breast cancer [ cosmic ]
S960 N960 Biomuta DOID:363 / uterine cancer [ icgc ]
S964 F964 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S964 Y964 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]