iPTMnet Report for P54709 (ATP1B3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P54709 / AT1B3_HUMAN
Protein Name Sodium/potassium-transporting ATPase subunit beta-3
Gene Name Name: ATP1B3
Organism Homo sapiens (Human)

PRO ID PR:P54709
DAG View
PRO Name sodium/potassium-transporting ATPase subunit beta-3 (human)
Definition A sodium/potassium-transporting ATPase subunit beta-3 that is encoded in the genome of human.
Short Label hATP1B3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54709 (ATP1B3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
T89 O-Glycosylation GlyGen 25813380
T101 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
N124 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T126 O-Glycosylation GlyGen 33214551, 34725712, 34019948, ...32870666, 32119511, 35289036
K137 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
N240 N-Glycosylation GlyGen   UniProt 29741879, 12754519, 24190977
N241 N-Glycosylation GlyGen 24190977
K251 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K86 R86 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S102 L102 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K194 N194 Biomuta DOID:363 / uterine cancer [ icgc ]
K221 T221 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
N240 D240 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K251 T251 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K259 R259 Biomuta DOID:4606 / bile duct cancer [ cosmic ]