iPTMnet Report for P53805 (RCAN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53805 / RCAN1_HUMAN
Protein Name Calcipressin-1
Gene Name Name: RCAN1
Synonyms:ADAPT78,CSP1,DSC1,DSCR1;
Organism Homo sapiens (Human)

PRO ID PR:P53805
DAG View
PRO Name calcipressin-1 (human)
Definition A calcipressin-1 that is encoded in the genome of human.
Short Label hRCAN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53805 (RCAN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K86 Ubiquitination PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
S163 Phosphorylation Q99759 (MAP3K3) , P49841 (GSK3B) PhosphoSitePlus   UniProt 16126726, 12809556, 21965663
S167 Phosphorylation Q99759 (MAP3K3) , Q13627 (DYRK1A) , P27361 (MAPK3) , P28482 (MAPK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16126726, 12809556, 21965663, ...12063245
T179 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
T247 Phosphorylation Q13627 (DYRK1A) neXtProt   PhosphoSitePlus 21965663
Site PTM Type PTM Enzyme Score Source PMID
S163 Phosphorylation P49841 (GSK3B) HPRD 19651622, 12063245, 20068231
S167 Phosphorylation P27361 (MAPK3) HPRD 19413330, 12063245, 19651622, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S93 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 25753203
S108 Phosphorylation P49841 (GSK3B) HPRD 19651622, 12063245, 20068231
S112 Phosphorylation P27361 (MAPK3) HPRD 19413330, 12063245, 19651622, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation P49841 (GSK3B) HPRD 19651622, 12063245, 20068231
S32 Phosphorylation P27361 (MAPK3) HPRD 19413330, 12063245, 19651622, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 Y32 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K86 R86 Biomuta [ cosmic ]
S112 Y112 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K128 T128 Biomuta DOID:363 / uterine cancer [ icgc ]
K128 E128 Biomuta DOID:1324 / lung cancer [ cosmic ]
S167 Y167 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y188 F188 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T208 I208 Biomuta DOID:363 / uterine cancer [ icgc ]
T247 M247 Biomuta DOID:9256 / colorectal cancer [ cosmic ]