Protein Information

Cytoscape View


UniProt AC / UniProt ID P53701 / CCHL_HUMAN
Protein Name Holocytochrome c-type synthase
Gene Name Name: HCCS
Synonyms:CCHL;
Organism Homo sapiens (Human)

PRO ID PR:P53701
DAG View
PRO Name holocytochrome c-type synthase (human)
Definition A holocytochrome c-type synthase that is encoded in the genome of human.
Short Label hHCCS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53701 (HCCS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805, 25807930
T39 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K145 Sumoylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
Y228 Phosphorylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T39 A39 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K163 E163 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S200 Y200 Biomuta DOID:363 / uterine cancer [ tcga ]