iPTMnet Report for P53677 (AP3M2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53677 / AP3M2_HUMAN
Protein Name AP-3 complex subunit mu-2
Gene Name Name: AP3M2
Organism Homo sapiens (Human)

PRO ID PR:P53677
DAG View
PRO Name AP-3 complex subunit mu-2 (human)
Definition An AP-3 complex subunit mu-2 that is encoded in the genome of human.
Short Label hAP3M2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53677 (AP3M2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C29 Methylation IEDB 31844290
Y31 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
C209 Methylation IEDB 31844290
R238 Methylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
T300 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C29 Y29 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y60 F60 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R238 C238 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R238 H238 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T300 M300 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K388 E388 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K413 T413 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]