iPTMnet Report for P53618 (COPB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53618 / COPB_HUMAN
Protein Name Coatomer subunit beta
Gene Name Name: COPB1
Synonyms:COPB;ORFNames:MSTP026;
Organism Homo sapiens (Human)

PRO ID PR:P53618
DAG View
PRO Name coatomer subunit beta (human)
Definition A coatomer subunit beta that is encoded in the genome of human.
Short Label hCOPB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53618 (COPB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 19413330, 22223895
T2 Phosphorylation HPRD   PhosphoSitePlus 18491316
T61 Phosphorylation PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
R117 Methylation PhosphoSitePlus
C125 Methylation IEDB 31844290
K126 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
Y160 Phosphorylation HPRD 20068231
T161 Phosphorylation HPRD   PhosphoSitePlus 20068231
C248 S-Nitrosylation dbSNO 19483679
T267 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
T276 Phosphorylation HPRD   PhosphoSitePlus 20068231
K291 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
R304 Methylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
K378 Acetylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
Y455 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
S491 Phosphorylation HPRD 20068231
K494 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
T516 Phosphorylation PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
Y521 Phosphorylation PhosphoSitePlus
T523 Phosphorylation PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
K633 Ubiquitination PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
K646 Ubiquitination PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
K685 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
S711 Phosphorylation HPRD   PhosphoSitePlus 20068231
K712 Ubiquitination PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
S773 Phosphorylation PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
Y865 Phosphorylation PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
K876 Ubiquitination PhosphoSitePlus
T879 Phosphorylation PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus
K913 Acetylation PhosphoSitePlus
K913 Ubiquitination PhosphoSitePlus
T924 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
K943 Ubiquitination PhosphoSitePlus
K949 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 M2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T61 I61 Biomuta DOID:1319 / brain cancer [ cosmic ]
R117 * Biomuta DOID:363 / uterine cancer [ cosmic ]
T270 S270 Biomuta DOID:3571 / liver cancer [ cosmic ]
T276 A276 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R304 C304 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
S451 C451 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T468 A468 Biomuta DOID:363 / uterine cancer [ icgc ]
T507 N507 Biomuta DOID:363 / uterine cancer [ icgc ]
K513 E513 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T523 A523 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S525 N525 Biomuta DOID:1324 / lung cancer [ cosmic ]
K646 N646 Biomuta DOID:263 / kidney cancer [ cosmic ]
K651 N651 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1612 / breast cancer [ cosmic ]