iPTMnet Report for P53611 (RABGGTB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53611 / PGTB2_HUMAN
Protein Name Geranylgeranyl transferase type-2 subunit beta
Gene Name Name: RABGGTB
Synonyms:GGTB;
Organism Homo sapiens (Human)

PRO ID PR:P53611
DAG View
PRO Name geranylgeranyl transferase type-2 subunit beta (human)
Definition A geranylgeranyl transferase type-2 subunit beta that is encoded in the genome of human.
Short Label hRABGGTB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53611 (RABGGTB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Acetylation UniProt 19413330, 20068231
T3 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...19413330, 18669648, 20068231
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
K11 Sumoylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
C148 Methylation IEDB 31844290
Y241 Phosphorylation PhosphoSitePlus
K307 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
G2 V2 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K33 N33 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:3953 / adrenal gland cancer [ cosmic ]