Protein Information

Cytoscape View


UniProt AC / UniProt ID P53582 / MAP11_HUMAN
Protein Name Methionine aminopeptidase 1
Gene Name Name: METAP1
Synonyms:KIAA0094;
Organism Homo sapiens (Human)

PRO ID PR:P53582
DAG View
PRO Name methionine aminopeptidase 1 (human)
Definition A methionine aminopeptidase 1 that is encoded in the genome of human.
Short Label hMETAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53582 (METAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K19 Ubiquitination PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K191 Sumoylation PhosphoSitePlus
Y253 Phosphorylation HPRD   PhosphoSitePlus 15592455, 20068231
K278 Ubiquitination PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 S2 Biomuta DOID:1115 / sarcoma [ tcga ]
S132 L132 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S384 F384 Biomuta DOID:1793 / pancreatic cancer [ tcga ]