iPTMnet Report for P53420 (COL4A4)
Protein Information
| UniProt AC / UniProt ID | P53420 / CO4A4_HUMAN |
| Protein Name | Collagen alpha-4(IV) chain precursor |
| Gene Name | Name: COL4A4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P53420 |
| PRO Name | collagen alpha-4(IV) chain (human) |
| Definition | A collagen alpha-4(IV) chain that is encoded in the genome of human. |
| Short Label | hCOL4A4 |
| Category | organism-gene |
P53420 (COL4A4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1229 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1403 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1425 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1540 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| Y1541 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S1545 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S1555 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| Y1562 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S1662 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1663 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1688 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S1403 | P1403 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| S1403 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| Y1541 | H1541 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View