iPTMnet Report for P53367 (ARFIP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53367 / ARFP1_HUMAN
Protein Name Arfaptin-1
Gene Name Name: ARFIP1
Organism Homo sapiens (Human)

PRO ID PR:P53367
DAG View
PRO Name arfaptin-1 (human)
Definition An arfaptin-1 that is encoded in the genome of human.
Short Label hARFIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53367 (ARFIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 21406692, 22814378, 20068231
S5 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S9 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus   UniProt 23186163
K34 Ubiquitination PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus   UniProt 24275569
S39 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S44 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S69 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S76 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S79 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S93 Phosphorylation PhosphoSitePlus
G100 Phosphorylation IntAct 23695357
K107 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
S132 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21406692, 23186163, 22981988, ...23695357, 18669648
S132 Phosphorylation Q15139 (PRKD1) PhosphoSitePlus   Signor 22981988, 23695357
T135 Phosphorylation PhosphoSitePlus
Y136 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus   UniProt 19690332
S368 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 20068231
S24 Phosphorylation HPRD 20068231
S28 Phosphorylation HPRD 20068231
S36 Phosphorylation HPRD 20166139
S39 Phosphorylation HPRD 19651622, 20166139
S69 Phosphorylation HPRD 18669648, 20068231
S76 Phosphorylation HPRD 18669648, 20068231
S79 Phosphorylation HPRD 18669648, 20068231
S93 Phosphorylation HPRD 20068231
S132 Phosphorylation HPRD 19413330, 18767875, 17322306, ...18669648, 18707149, 20068231
T253 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 20068231
S24 Phosphorylation HPRD 20068231
S28 Phosphorylation HPRD 20068231
S36 Phosphorylation HPRD 20166139
S39 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20166139
K57 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S100 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18767875, 23695357, ...17322306, 18669648, 18707149, 20068231
S100 Phosphorylation Q15139 (PRKD1) PhosphoSitePlus 23695357
T221 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 I28 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S28 N28 Biomuta DOID:4159 / skin cancer [ cosmic ]
S36 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S44 L44 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S69 F69 Biomuta DOID:4159 / skin cancer [ cosmic, cosmic ] [ cosmic ] DOID:1115 / sarcoma [ icgc ] DOID:263 / kidney cancer [ cosmic ]
Y304 H304 Biomuta DOID:363 / uterine cancer [ icgc ]
K322 T322 Biomuta DOID:2998 / testicular cancer [ cosmic ]