iPTMnet Report for P53365 (ARFIP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53365 / ARFP2_HUMAN
Protein Name Arfaptin-2
Gene Name Name: ARFIP2
Synonyms:POR1;
Organism Homo sapiens (Human)

PRO ID PR:P53365
DAG View
PRO Name arfaptin-2 (human)
Definition An arfaptin-2 that is encoded in the genome of human.
Short Label hARFIP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53365 (ARFIP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus   UniProt 23186163
S74 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus   UniProt 23186163
R86 Methylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
T103 Phosphorylation PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
Y235 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S260 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 15809304
S260 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   Signor 15809304
K284 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S72 Phosphorylation HPRD 20068231
T76 Phosphorylation HPRD 20068231
T103 Phosphorylation HPRD 18212344


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S74 R74 Biomuta DOID:3571 / liver cancer [ cosmic ]
S74 N74 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R86 W86 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K92 Q92 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y104 C104 Biomuta DOID:2531 / hematologic cancer [ cosmic ]