iPTMnet Report for P53350 (PLK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53350 / PLK1_HUMAN
Protein Name Serine/threonine-protein kinase PLK1
Gene Name Name: PLK1
Synonyms:PLK;
Organism Homo sapiens (Human)

PRO ID PR:P53350
DAG View
PRO Name serine/threonine-protein kinase PLK1 (human)
Definition A serine/threonine-protein kinase PLK1 that is encoded in the genome of human.
Short Label hPLK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53350 (PLK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation HPRD   PhosphoSitePlus 20068231
T6 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   UniProt 18691976
K9 Acetylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus   UniProt 18662541
K38 Ubiquitination PhosphoSitePlus
S49 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18427546
S49 Phosphorylation Q13153 (PAK1) neXtProt   PhosphoSitePlus   Signor 18427546
K61 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S99 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P 23695676, 29753186
S103 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   UniProt 18691976
S137 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18551195, 19804365, 34197606, ...15713655, 31548612, 26919439, 15611664, 30789735, 19706541, 12207013
S137 Phosphorylation P41279 (MAP3K8) PhosphoSitePlus 19804365
S137 Phosphorylation Q13237 (PRKG2) neXtProt 18551195
S137 Phosphorylation Q9NYY3 (PLK2) neXtProt   PhosphoSitePlus 19706541
K143 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K191 Methylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K209 Methylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
T210 Phosphorylation HPRD   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 22686412, 15713655, 22641346, ...24785407, 33754208, 30069007, 20869364, 18477460, 27568005, 33402344, 33262323, 26057687, 26114094, 29962965, 33771996, 22753416, 18691976, 23186163, 25245035, 32575753, 31863092, 24722282, 25607646, 20656208, 24152729, 31548612, 36231009, 29154753, 33805672, 24338364, 12207013, 24204733, 30854428, 26259146, 23695676, 18560274, 21739483, 26242183, 31156720, 34197606, 25563361, 15611664, 26206521, 27504491, 19804365, 27603133, 25965828, 31031853, 22566210, 19369195, 27721411, 26820885, 22701722, 29976560, 18615013, 25246616, 31597699, 27965426, 17322306, 20373286, 18669648, 30789735, 20068231
T210 Phosphorylation O14965 (AURKA) neXtProt   PhosphoSitePlus   RLIMS-P+   Signor 12207013, 18615013, 24338364, ...20869364
T210 Phosphorylation O94804 (STK10) PhosphoSitePlus 12207013
T210 Phosphorylation P41279 (MAP3K8) PhosphoSitePlus   Signor 12207013, 19804365
T210 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus 26206521
T214 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 19369195, 26919439, ...18669648, 20068231
Y217 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
S280 Phosphorylation RLIMS-P 29976560
K284 Methylation PhosphoSitePlus
T288 Phosphorylation RLIMS-P 33754208, 33771996
T291 O-Glycosylation GlyGen 28510447, 36626982, 22564745
Y309 Phosphorylation PhosphoSitePlus
S326 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18695677
S326 Phosphorylation P49137 (MAPKAPK2) neXtProt   PhosphoSitePlus   Signor 18695677
S330 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 18691976, 22202082
S331 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus   UniProt 12442251
K338 Ubiquitination PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
C372 Methylation IEDB 31844290
S375 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   UniProt 18691976
S383 Phosphorylation neXtProt   PhosphoSitePlus 18695677
S383 Phosphorylation P49137 (MAPKAPK2) neXtProt   PhosphoSitePlus 18695677
S387 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K388 Methylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K413 Methylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
S418 Phosphorylation RLIMS-P 19543530
K420 Methylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus   Signor 27899378
Y425 Phosphorylation P00519 (ABL1) Signor 27899378
Y445 Phosphorylation PhosphoSitePlus
S450 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   UniProt 18691976
T459 Phosphorylation PhosphoSitePlus
S461 Phosphorylation HPRD   neXtProt   PhosphoSitePlus 18691976
Y462 Phosphorylation PhosphoSitePlus
T464 Phosphorylation HPRD   neXtProt   PhosphoSitePlus 18691976
S466 Phosphorylation PhosphoSitePlus
K474 Methylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K492 Sumoylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus   UniProt 23455478
T498 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   UniProt 18691976
K540 Methylation PhosphoSitePlus
C544 Methylation IEDB 31844290
S565 Phosphorylation PhosphoSitePlus
K574 Methylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
K589 Ubiquitination PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus   RLIMS-P 22202082


P53350 (PLK1) as PTM Enzyme



Substrate Site Score Source PMID
O00139 (KIF2A) T554 PhosphoSitePlus 25660017
O14641 (DVL2) T206 PhosphoSitePlus   Signor 20823832
O14920 (IKBKB) S733 neXtProt   PhosphoSitePlus   Signor 18957422
O14920 (IKBKB) S740 neXtProt   PhosphoSitePlus   Signor 18957422
O14920 (IKBKB) S750 neXtProt   PhosphoSitePlus   Signor 18957422
O15169 (AXIN1) S157 RLIMS-P+ 23155463
O15259 (NPHP1) T87 neXtProt 22701722
O15350 (TP73) T27 neXtProt   PhosphoSitePlus   Signor 18418051, 18174154
O15392 (BIRC5) S20 PhosphoSitePlus   Signor 21148584, 20427271
O15392 (BIRC5) T21 PhosphoSitePlus 21148584, 20427271
O43663 (PRC1) S615 PhosphoSitePlus 17351640
O43663 (PRC1) T616 PhosphoSitePlus 22621898, 24120663
O60260 (PRKN) S378 PhosphoSitePlus 26387737
O60285 (NUAK1) S476 RLIMS-P+ 24785407
O60285 (NUAK1) S480 RLIMS-P+ 24785407
O60563 (CCNT1) S564 PhosphoSitePlus 23977272
O60566 (BUB1B) S676 phospho.ELM   PhosphoSitePlus   Signor 17785528
O60566 (BUB1B) T680 PhosphoSitePlus   Signor 23079597
O60566 (BUB1B) T792 neXtProt   PhosphoSitePlus   Signor 17376779
O60566 (BUB1B) T1008 neXtProt   PhosphoSitePlus   Signor 17376779
O75116 (ROCK2) T967 neXtProt 17446864
O75116 (ROCK2) S1099 neXtProt 17446864
O75116 (ROCK2) S1133 neXtProt 17446864
O75116 (ROCK2) S1374 neXtProt 17446864
O94901 (SUN1) S138 RLIMS-P+   Signor 25482198
O95251 (KAT7) S57 PhosphoSitePlus   Signor 18250300
O95425 (SVIL) S238 PhosphoSitePlus 23750008
O95613 (PCNT) T1209 PhosphoSitePlus 22184200
O95613 (PCNT) T1221 PhosphoSitePlus 22184200
O95613 (PCNT) S1235 PhosphoSitePlus 22184200
O95613 (PCNT) S1241 PhosphoSitePlus 22184200
O96017-1 (CHEK2) T26 HPRD   phospho.ELM 10973490, 12493754, 12024051
O96017 (CHEK2) T68 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10973490, 20126263, 11901158, ...12493754, 12242661
O96017 (CHEK2) S164 PhosphoSitePlus 20126263
O96017 (CHEK2) T205 PhosphoSitePlus 20126263
O96017 (CHEK2) S210 PhosphoSitePlus 20126263
P04049 (RAF1) S338 RLIMS-P+ 27003818
P04049 (RAF1) S339 RLIMS-P+ 27003818
P06748 (NPM1) S4 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 19413330, 19651622, 15190079, ...20352051, 20068231
P08670 (VIM) S83 PhosphoSitePlus   Signor 18056432
P08670 (VIM) S459 RLIMS-P+ 24196446
P11388 (TOP2A) S1337 PhosphoSitePlus   Signor 18171681
P11388 (TOP2A) T1343 PhosphoSitePlus 18062778
P11388 (TOP2A) S1525 PhosphoSitePlus   Signor 19098900, 18171681
P11413 (G6PD) T406 Signor 29138396
P11413 (G6PD) T466 Signor 29138396
P13693-1 (TPT1) S46 HPRD   phospho.ELM   RLIMS-P+   Signor 21187478, 12167714, 18669648, ...17287340, 20068231
P13693 (TPT1) S64 HPRD   phospho.ELM   Signor 12167714
P14635-1 (CCNB1) S126 HPRD   phospho.ELM   PhosphoSitePlus   Signor 12447691, 11242082
P14635 (CCNB1) S128 HPRD   phospho.ELM   PhosphoSitePlus   Signor 12447691, 11242082
P14635 (CCNB1) S133 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11242082, 12447691, 12524548, ...18062778
P14635 (CCNB1) S147 HPRD   phospho.ELM   PhosphoSitePlus   Signor 11242082
P18031 (PTPN1) S286 PhosphoSitePlus   Signor 23348582
P18031 (PTPN1) S393 PhosphoSitePlus 23348582
P25490 (YY1) T39 PhosphoSitePlus   Signor 23226345, 21253604
P30260 (CDC27) T205 PhosphoSitePlus 14657031
P30260 (CDC27) T209 phospho.ELM   PhosphoSitePlus 14657031
P30260 (CDC27) S426 PhosphoSitePlus 14657031
P30260 (CDC27) T430 phospho.ELM   PhosphoSitePlus 14657031
P30260 (CDC27) S434 phospho.ELM   PhosphoSitePlus 14657031
P30260 (CDC27) S435 PhosphoSitePlus 14657031
P30260 (CDC27) T446 phospho.ELM   PhosphoSitePlus 14657031
P30291 (WEE1) S53 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 15070733, 15350223, 16085715
P30291 (WEE1) S123 Signor 16085715
P30305 (CDC25B) S50 PhosphoSitePlus 21640712
P30305 (CDC25B) T58 PhosphoSitePlus 21640712
P30305 (CDC25B) T127 PhosphoSitePlus 21640712
P30305 (CDC25B) T167 PhosphoSitePlus 21640712
P30305 (CDC25B) S209 PhosphoSitePlus 21640712
P30305 (CDC25B) T265 PhosphoSitePlus 21640712
P30305 (CDC25B) S291 PhosphoSitePlus 21640712
P30305 (CDC25B) S353 PhosphoSitePlus 21640712
P30305 (CDC25B) S375 PhosphoSitePlus 21640712
P30305 (CDC25B) S397 PhosphoSitePlus 21640712
P30305 (CDC25B) T404 PhosphoSitePlus 21640712
P30305 (CDC25B) S465 PhosphoSitePlus 21640712
P30305 (CDC25B) S513 PhosphoSitePlus 21640712
P30307-1 (CDC25C) S198 HPRD   phospho.ELM   PhosphoSitePlus   Signor 11897663, 18062778
P30622 (CLIP1) S195 PhosphoSitePlus   Signor 20664522
P30622 (CLIP1) S312 PhosphoSitePlus 24451569
P30622 (CLIP1) S1364 PhosphoSitePlus 20664522
P30626 (SRI) T155 PhosphoSitePlus   Signor 24427308
P35222 (CTNNB1) S718 PhosphoSitePlus   Signor 19001871
P35568 (IRS1) S24 phospho.ELM   PhosphoSitePlus   Signor 15849359
P36507 (MAP2K2) S222 PhosphoSitePlus 26242183
P36507 (MAP2K2) S226 PhosphoSitePlus 26242183
P36956 (SREBF1) S467 RLIMS-P+ 27579997
P37840 (SNCA) S129 PhosphoSitePlus   Signor 19889641
P38398 (BRCA1) S1164 PhosphoSitePlus 26745677
P47736 (RAP1GAP) S525 PhosphoSitePlus   Signor 25329897
P49959 (MRE11) S649 Signor 28512243
P51587 (BRCA2) S193 HPRD   phospho.ELM   PhosphoSitePlus   Signor 24448238, 12815053
P51587 (BRCA2) T203 PhosphoSitePlus   Signor 12815053
P51587 (BRCA2) S205 PhosphoSitePlus   Signor 12815053
P51587 (BRCA2) S206 PhosphoSitePlus   Signor 12815053
P51587 (BRCA2) T207 PhosphoSitePlus   Signor 12815053
P51587 (BRCA2) S239 HPRD 12815053
P54274 (TERF1) S435 PhosphoSitePlus   Signor 18625707
P60484 (PTEN) S380 PhosphoSitePlus 24706748
P60484 (PTEN) T382 PhosphoSitePlus 24706748
P60484 (PTEN) T383 PhosphoSitePlus 24706748
P62826 (RAN) S135 PhosphoSitePlus   Signor 16930555
P78527 (PRKDC) S3205 RLIMS-P+ 24844881
Q00613 (HSF1) S216 PhosphoSitePlus   Signor 18794143, 19934326
Q00839 (HNRNPU) S59 PhosphoSitePlus 25986610
Q00987 (MDM2) S260 PhosphoSitePlus   Signor 19833129, 12383858
Q01538-1 (MYT1) S429 HPRD 12738781
Q02750 (MAP2K1) S218 PhosphoSitePlus 26242183
Q02750 (MAP2K1) S222 PhosphoSitePlus 26242183
Q06609 (RAD51) S14 neXtProt   PhosphoSitePlus 22325354, 24835992
Q07817 (BCL2L1) S62 PhosphoSitePlus   RLIMS-P+ 22617334, 24621501
Q08050 (FOXM1) S730 PhosphoSitePlus   Signor 19737929, 19160488
Q08050 (FOXM1) S739 PhosphoSitePlus   Signor 19737929, 19160488
Q12834 (CDC20) S170 RLIMS-P+ 23643811
Q12888 (TP53BP1) S1618 PhosphoSitePlus 25607646
Q13042 (CDC16) S112 PhosphoSitePlus 14657031
Q13158 (FADD) S194 PhosphoSitePlus   Signor 20890306, 21978935
Q13188 (STK3) S15 neXtProt 21723128
Q13188 (STK3) S18 neXtProt 21723128
Q13188 (STK3) S316 neXtProt 21723128
Q13416 (ORC2) S188 PhosphoSitePlus 21947279
Q13526 (PIN1) S65 phospho.ELM   PhosphoSitePlus   Signor 16118204
Q14203 (DCTN1) S179 PhosphoSitePlus   Signor 20679239
Q14674 (ESPL1) T1363 PhosphoSitePlus 17974570
Q14674 (ESPL1) S1399 PhosphoSitePlus 17974570
Q15013 (MAD2L1BP) S102 Signor 31118282
Q15022 (SUZ12) S539 PhosphoSitePlus 25855382
Q15022 (SUZ12) S541 PhosphoSitePlus 25855382
Q15022 (SUZ12) S546 PhosphoSitePlus 25855382
Q15468 (STIL) S1108 PhosphoSitePlus 26101219
Q15468 (STIL) S1116 PhosphoSitePlus 26101219
Q16143 (SNCB) S118 PhosphoSitePlus   Signor 19889641
Q2M2Z5 (KIZ) T379 neXtProt   PhosphoSitePlus   Signor 16980960
Q2NKX8 (ERCC6L) T1063 PhosphoSitePlus 17218258
Q38SD2 (LRRK1) S1817 PhosphoSitePlus 26192437
Q3KR16 (PLEKHG6) T574 PhosphoSitePlus   Signor 18694934
Q49MG5 (MAP9) S289 PhosphoSitePlus   Signor 20615875
Q53EZ4 (CEP55) S436 HPRD   PhosphoSitePlus   Signor 19413330, 16964243, 19664994, ...19691289, 18669648, 16198290, 20068231
Q5FBB7 (SGO1) S73 neXtProt 18331714
Q5FBB7 (SGO1) T146 neXtProt 18331714
Q6PGQ7 (BORA) S497 neXtProt   PhosphoSitePlus   Signor 18521620, 18378770
Q6PGQ7 (BORA) T501 neXtProt   PhosphoSitePlus   Signor 18521620, 18378770
Q71F23 (CENPU) S77 PhosphoSitePlus   Signor 17081991
Q71F23 (CENPU) T78 neXtProt   PhosphoSitePlus   Signor 17081991
Q7L2Z9 (CENPQ) T123 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) T135 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) S138 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) S139 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) S248 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) S249 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) S253 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) S255 PhosphoSitePlus   Signor 25670858
Q7L2Z9 (CENPQ) T256 PhosphoSitePlus   Signor 25670858
Q8IWB6 (TEX14) S437 PhosphoSitePlus   Signor 22405274
Q8N4N8 (KIF2B) T125 neXtProt   PhosphoSitePlus   Signor 22535524
Q8N4N8 (KIF2B) S204 neXtProt   PhosphoSitePlus   Signor 22535524
Q8NHV4 (NEDD1) T382 PhosphoSitePlus   Signor 19509060
Q8NHV4 (NEDD1) S397 PhosphoSitePlus   Signor 19509060
Q8NHV4 (NEDD1) S426 PhosphoSitePlus   Signor 19509060
Q8NHV4 (NEDD1) S637 PhosphoSitePlus   Signor 19509060
Q8TEP8 (CEP192) T44 PhosphoSitePlus   Signor 26012549
Q92994 (BRF1) S450 PhosphoSitePlus 22281053
Q96BK5 (PINX1) S110 PhosphoSitePlus   Signor 20573420
Q96BK5 (PINX1) S117 PhosphoSitePlus   Signor 20573420
Q96BK5 (PINX1) T141 PhosphoSitePlus   Signor 20573420
Q96BK5 (PINX1) S226 PhosphoSitePlus   Signor 20573420
Q96BK5 (PINX1) T317 PhosphoSitePlus   Signor 20573420
Q96CV9 (OPTN) S177 PhosphoSitePlus   Signor 22365832
Q96T23 (RSF1) S1359 PhosphoSitePlus   Signor 26259146
Q99640 (PKMYT1) S426 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12738781
Q99640 (PKMYT1) T495 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12738781, 18691976
Q99661 (KIF2C) S592 neXtProt 21078677
Q99661 (KIF2C) S595 neXtProt   RLIMS-P+ 21078677, 25504441
Q99661 (KIF2C) S621 neXtProt   RLIMS-P+ 21078677, 25504441, 24931513
Q99661 (KIF2C) S632 neXtProt   RLIMS-P+ 21078677, 25504441
Q99661 (KIF2C) S633 neXtProt   RLIMS-P+ 21078677, 25504441
Q99661 (KIF2C) S715 neXtProt   PhosphoSitePlus   RLIMS-P+ 21078677, 25504441, 26206521
Q99741 (CDC6) T37 PhosphoSitePlus   Signor 21041660
Q9BQQ3 (GORASP1) S189 PhosphoSitePlus 22523075
Q9BVS4 (RIOK2) S335 neXtProt   PhosphoSitePlus 21880710
Q9BVS4 (RIOK2) S380 neXtProt   PhosphoSitePlus 21880710
Q9BVS4 (RIOK2) S548 neXtProt   PhosphoSitePlus 21880710
Q9H0H5 (RACGAP1) S149 neXtProt 19468302, 19468300
Q9H0H5 (RACGAP1) S157 neXtProt   PhosphoSitePlus   Signor 19468302, 19468300
Q9H0H5 (RACGAP1) S164 neXtProt   PhosphoSitePlus 19468302, 19468300
Q9H0H5 (RACGAP1) S170 neXtProt   PhosphoSitePlus   Signor 19468302, 19468300
Q9H0H5 (RACGAP1) S214 neXtProt   PhosphoSitePlus   Signor 19468302, 19468300
Q9H0H5 (RACGAP1) T260 neXtProt   PhosphoSitePlus   Signor 19468302, 19468300
Q9H1A4 (ANAPC1) T291 phospho.ELM   PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) S355 phospho.ELM   PhosphoSitePlus   Signor 14657031
Q9H1A4 (ANAPC1) S373 PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) S377 phospho.ELM   PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) T520 phospho.ELM   PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) T530 phospho.ELM   PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) S547 PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) S686 phospho.ELM 14657031
Q9H1A4 (ANAPC1) S688 phospho.ELM   PhosphoSitePlus 14657031
Q9H1A4 (ANAPC1) T701 PhosphoSitePlus 14657031
Q9H2D6 (TRIOBP) T447 Signor 22820163
Q9H2D6-5 (TRIOBP) T457 PhosphoSitePlus 22820163, 24692559
Q9H2D6 (TRIOBP) T2229 Signor 22820163
Q9H8V3-4 (ECT2) T815 HPRD 18669648, 16247472
Q9HAW4 (CLSPN) S30 neXtProt   PhosphoSitePlus   Signor 16885021, 16885022, 16934469
Q9NS56 (TOPORS) S718 neXtProt   PhosphoSitePlus   Signor 19473992
Q9NYZ3 (GTSE1) S223 PhosphoSitePlus 20577264
Q9NYZ3 (GTSE1) S435 PhosphoSitePlus   Signor 20577264
Q9UBB4 (ATXN10) S77 neXtProt   PhosphoSitePlus   Signor 21857149
Q9UBB4 (ATXN10) T82 neXtProt   PhosphoSitePlus   Signor 21857149
Q9UBW7 (ZMYM2) S303 PhosphoSitePlus 25855382
Q9UBW7 (ZMYM2) S305 PhosphoSitePlus 25855382
Q9UBW7 (ZMYM2) S309 PhosphoSitePlus 25855382
Q9UJX2 (CDC23) T562 PhosphoSitePlus 14657031
Q9UJX2 (CDC23) T565 PhosphoSitePlus 14657031
Q9UJX3 (ANAPC7) S17 phospho.ELM 14657031
Q9UJX3 (ANAPC7) S23 phospho.ELM 14657031
Q9UJX3 (ANAPC7) S30 phospho.ELM 14657031
Q9UJX3 (ANAPC7) S64 PhosphoSitePlus 14657031
Q9UJX5 (ANAPC4) S779 phospho.ELM   PhosphoSitePlus 14657031
Q9UKT4 (FBXO5) S145 neXtProt   PhosphoSitePlus 15469984, 15148369
Q9UKT4 (FBXO5) S149 neXtProt   PhosphoSitePlus 15469984, 15148369
Q9Y265 (RUVBL1) T239 PhosphoSitePlus 26201077
Q9Y266 (NUDC) S274 HPRD   phospho.ELM   PhosphoSitePlus   Signor 12852857
Q9Y266 (NUDC) S326 HPRD   phospho.ELM   PhosphoSitePlus   Signor 12852857
Q9Y2I6 (NINL) S87 phospho.ELM   PhosphoSitePlus 12852856
Q9Y2I6 (NINL) S88 phospho.ELM   PhosphoSitePlus 12852856
Q9Y2I6 (NINL) T161 HPRD   phospho.ELM   PhosphoSitePlus 12852856
Q9Y2I6 (NINL) S686 HPRD   phospho.ELM   PhosphoSitePlus 12852856
Q9Y2T1 (AXIN2) S311 PhosphoSitePlus 26438599
Q9Y2Z0 (SUGT1) S331 PhosphoSitePlus   Signor 22869522
Q9Y5T5 (USP16) S330 PhosphoSitePlus 26323689
Q9Y5T5 (USP16) S386 PhosphoSitePlus 26323689
Q9Y5T5 (USP16) S486 PhosphoSitePlus 26323689
Q9Y6D9 (MAD1L1) S22 PhosphoSitePlus 18922800
Q9Y6D9 (MAD1L1) S29 PhosphoSitePlus 18922800
Q9Y6D9 (MAD1L1) T680 PhosphoSitePlus 18922800


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000044818 (hPLK1/Phos:1) pS99,pT210 PRO 23695676
PR:000048813 (hPLK1/Phos:3) pT210 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O43683 (BUB1) T609 P53350 (PLK1) unknown eFIP 26912231
Phosphorylation O60285 (NUAK1) S445 P53350 (PLK1) unknown eFIP 24785407
Phosphorylation O75122 (CLASP2) S1234 P53350 (PLK1) unknown eFIP 23045552
Phosphorylation P08670 (VIM) S55 P53350 (PLK1) unknown eFIP 16260496
Phosphorylation P10244 (MYBL2) T476 P53350 (PLK1) unknown eFIP 30321399
Phosphorylation P30291 (WEE1) S139 P53350 (PLK1) inhibited_association eFIP 23051732
Phosphorylation P51587 (BRCA2) T77 P53350 (PLK1) unknown eFIP 32286328
Phosphorylation P53350 (PLK1) T210 Q6PGQ7 (BORA) unknown eFIP 27721411
Phosphorylation P53350 (PLK1) S99 P61981 (YWHAG) unknown eFIP 23695676
Phosphorylation P53350 (PLK1) S597 P63104 (YWHAZ) increased_association eFIP 22202082
Phosphorylation Q14511 (NEDD9) S780 P53350 (PLK1) increased_association eFIP 29191835
Phosphorylation Q3KR16 (PLEKHG6) T544 P53350 (PLK1) increased_association eFIP 24482237
Phosphorylation Q53EZ4 (CEP55) S436 P53350 (PLK1) unknown eFIP 16198290
Phosphorylation Q8IX90 (SKA3) T360 P53350 (PLK1) unknown eFIP 33106477
Phosphorylation Q99638 (RAD9A) T292 P53350 (PLK1) unknown eFIP 29254517


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000035362 (hBUB1B/Phos:1) increased Interaction PR:P53350 (hPLK1) PRO 17785528
PR:000035373 (hBUB1B/PhosRes-) Interaction PR:000035669 (hPLK1/PhosRes-) PRO 19503101
PR:000035405 (hBUB1/PhosRes-) NOT Interaction PR:P53350 (hPLK1) PRO 16760428
PR:000044818 (hPLK1/Phos:1) Interaction PR:P61981 (hYWHAG) PRO 23695676
PR:O14641 (hDVL2) Interaction PR:P53350 (hPLK1) PRO 20823832
PR:O43683 (hBUB1) Interaction PR:P53350 (hPLK1) PRO
PR:P53350 (hPLK1) Interaction PR:O14641 (hDVL2) PRO 20823832
PR:P53350 (hPLK1) Interaction PR:Q5FBB7 (hSGO1) PRO
PR:P53350 (hPLK1) Interaction PR:O43683 (hBUB1) PRO
PR:P53350 (hPLK1) Interaction PR:O60566 (hBUB1B) PRO 17376779
PR:Q5FBB7 (hSGO1) Interaction PR:P53350 (hPLK1) PRO