iPTMnet Report for P53007 (SLC25A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53007 / TXTP_HUMAN
Protein Name Tricarboxylate transport protein, mitochondrial precursor
Gene Name Name: SLC25A1
Synonyms:SLC20A3;
Organism Homo sapiens (Human)

PRO ID PR:P53007
DAG View
PRO Name tricarboxylate transport protein, mitochondrial (human)
Definition A tricarboxylate transport protein, mitochondrial that is encoded in the genome of human.
Short Label hSLC25A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53007 (SLC25A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
R65 Methylation PhosphoSitePlus
C70 S-Nitrosylation dbSNO 24105792
K97 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus   UniProt 23186163
K160 Acetylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K178 Methylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
Y256 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y276 Phosphorylation PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R65 W65 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K160 N160 Biomuta DOID:2394 / ovarian cancer [ icgc ]
K190 R190 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y297 C297 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]