Protein Information

Cytoscape View


UniProt AC / UniProt ID P52907 / CAZA1_HUMAN
Protein Name F-actin-capping protein subunit alpha-1
Gene Name Name: CAPZA1
Organism Homo sapiens (Human)

PRO ID PR:P52907
DAG View
PRO Name F-actin-capping protein subunit alpha-1 (human)
Definition An F-actin-capping protein subunit alpha-1 that is encoded in the genome of human.
Short Label hCAPZA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52907 (CAPZA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
R7 Methylation PhosphoSitePlus
S9 Phosphorylation P68400 (CSNK2A1) HPRD   PhosphoSitePlus   Signor   UniProt 23186163, 19691289, 19651622, ...15831458, 20068231
K13 Ubiquitination PhosphoSitePlus
K19 Acetylation PhosphoSitePlus   UniProt 19608861
K19 Ubiquitination PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
K97 Acetylation PhosphoSitePlus   UniProt 19608861
K97 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
S160 O-Glycosylation GlyGen 30444036, 29351928, 30397120
K166 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
K256 Methylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K268 Sumoylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
K273 Sumoylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K278 Acetylation PhosphoSitePlus
K278 Sumoylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R7 L7 Biomuta DOID:3571 / liver cancer [ icgc ]
R7 C7 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K256 T256 Biomuta DOID:363 / uterine cancer [ tcga ]
K268 E268 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]