Protein Information

Cytoscape View


UniProt AC / UniProt ID P52790 / HXK3_HUMAN
Protein Name Hexokinase-3
Gene Name Name: HK3
Organism Homo sapiens (Human)

PRO ID PR:P52790
DAG View
PRO Name hexokinase-3 (human)
Definition A hexokinase-3 that is encoded in the genome of human.
Short Label hHK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52790 (HK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S67 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
R677 Methylation PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
Y755 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S67 N67 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R677 H677 Biomuta DOID:10283 / prostate cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
R677 C677 Biomuta DOID:3571 / liver cancer [ icgc ]