iPTMnet Report for P52757 (CHN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P52757 / CHIO_HUMAN
Protein Name Beta-chimaerin
Gene Name Name: CHN2
Synonyms:ARHGAP3,BCH;
Organism Homo sapiens (Human)

PRO ID PR:P52757
DAG View
PRO Name beta-chimaerin (human)
Definition A beta-chimaerin that is encoded in the genome of human.
Short Label hCHN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52757 (CHN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
Y21 Phosphorylation P06241 (FYN) , P12931 (SRC) PhosphoSitePlus   Signor 17560670
Y153 Phosphorylation P06239 (LCK) PhosphoSitePlus 19201754
Y158 Phosphorylation PhosphoSitePlus
T160 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S171 Phosphorylation Q05655 (PRKCD) neXtProt   PhosphoSitePlus   Signor 20335173
S173 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P21860 (ERBB3) Y1276 P52757 (CHN2) unknown eFIP 16273093


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K192 E192 Biomuta DOID:11934 / head and neck cancer [ tcga ]
K334 R334 Biomuta DOID:263 / kidney cancer [ tcga ]
K334 N334 Biomuta DOID:3070 / malignant glioma [ tcga ]