Protein Information

Cytoscape View


UniProt AC / UniProt ID P52569 / CTR2_HUMAN
Protein Name Cationic amino acid transporter 2
Gene Name Name: SLC7A2
Synonyms:ATRC2,CAT2;
Organism Homo sapiens (Human)

PRO ID PR:P52569
DAG View
PRO Name cationic amino acid transporter 2 (human)
Definition A cationic amino acid transporter 2 that is encoded in the genome of human.
Short Label hSLC7A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52569 (SLC7A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus   UniProt 23186163
T28 Phosphorylation PhosphoSitePlus   UniProt 23186163
K29 Ubiquitination PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
N227 N-Glycosylation GlyGen 24190977
S415 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus   UniProt 23186163
K449 Ubiquitination PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus   UniProt 20068231
K461 Ubiquitination PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus   UniProt 23186163
T467 Phosphorylation PhosphoSitePlus
Y621 Phosphorylation PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
S646 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S647 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K654 Sumoylation PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S455 Phosphorylation HPRD 20068231
S646 Phosphorylation HPRD 20166139, 18669648, 20068231
S647 Phosphorylation HPRD 18767875, 18669648
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S494 Phosphorylation HPRD 20068231
S685 Phosphorylation HPRD 20166139, 18669648, 20068231
S686 Phosphorylation HPRD 18767875, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S415 P415 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S415 F415 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S454 L454 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]