iPTMnet Report for P52569 (SLC7A2)
Protein Information
| UniProt AC / UniProt ID | P52569 / CTR2_HUMAN |
| Protein Name | Cationic amino acid transporter 2 |
| Gene Name | Name: SLC7A2 Synonyms:ATRC2,CAT2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P52569 |
| PRO Name | cationic amino acid transporter 2 (human) |
| Definition | A cationic amino acid transporter 2 that is encoded in the genome of human. |
| Short Label | hSLC7A2 |
| Category | organism-gene |
DAG ViewP52569 (SLC7A2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S24 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T28 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N227 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S382 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S415 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y422 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y440 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S446 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K449 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S454 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S455 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| K461 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S462 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S464 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y621 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K632 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S633 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S646 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 24275569 | ||
| S647 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| K654 | Sumoylation | score1 | PhosphoSitePlus | |||
| K654 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S455 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S646 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 20068231 | ||
| S647 | Phosphorylation | score0 | HPRD | 18767875, 18669648 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S494 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S685 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 20068231 | ||
| S686 | Phosphorylation | score0 | HPRD | 18767875, 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S382 | F382 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S415 | F415 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S454 | L454 | Biomuta | [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S633 | Y633 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S647 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S647 | L647 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S686 | L686 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S686 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
