iPTMnet Report for P52435 (POLR2J)
Protein Information
| UniProt AC / UniProt ID | P52435 / RPB11_HUMAN |
| Protein Name | DNA-directed RNA polymerase II subunit RPB11-a |
| Gene Name | Name: POLR2J Synonyms:POLR2J1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P52435 |
| PRO Name | DNA-directed RNA polymerase II subunit RPB11-a (human) |
| Definition | A DNA-directed RNA polymerase II subunit RPB11-a that is encoded in the genome of human. |
| Short Label | hPOLR2J |
| Category | organism-gene |
DAG ViewP52435 (POLR2J) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K62 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K110 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T41 | I41 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K52 | E52 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] |
