iPTMnet Report for P51965 (UBE2E1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51965 / UB2E1_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 E1
Gene Name Name: UBE2E1
Synonyms:UBCH6;
Organism Homo sapiens (Human)

PRO ID PR:P51965
DAG View
PRO Name ubiquitin-conjugating enzyme E2 E1 (human)
Definition A ubiquitin-conjugating enzyme E2 E1 that is encoded in the genome of human.
Short Label hUBE2E1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51965 (UBE2E1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692
S2 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K43 Sumoylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
C131 Methylation IEDB 31844290
K136 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 19413330
S9 Phosphorylation HPRD 19413330
S12 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 19413330
S9 Phosphorylation HPRD 19413330
S12 Phosphorylation HPRD 19413330
K55 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K43 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K54 N54 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]