iPTMnet Report P51948 MNAT1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P51948 / MAT1_HUMAN
Protein Name	CDK-activating kinase assembly factor MAT1
Gene Name	Name: MNAT1 Synonyms:CAP35,MAT1,RNF66;
Organism	Homo sapiens (Human)

PRO ID	PR:P51948 DAG View
PRO Name	CDK-activating kinase assembly factor MAT1 (human)
Definition	A CDK-activating kinase assembly factor MAT1 that is encoded in the genome of human.
Short Label	hMNAT1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P51948 (MNAT1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	UniProt	19413330
	Y14	Phosphorylation		score1	PhosphoSitePlus
	S18	Phosphorylation		score1	PhosphoSitePlus
	T51	Phosphorylation		score2	PhosphoSitePlus UniProt	18691976
	K70	Ubiquitination		score1	PhosphoSitePlus
	K167	Ubiquitination		score1	PhosphoSitePlus
	K176	Ubiquitination		score1	PhosphoSitePlus
	K180	Ubiquitination		score1	PhosphoSitePlus
	K202	Ubiquitination		score1	PhosphoSitePlus
	S205	Phosphorylation		score1	PhosphoSitePlus
	K219	Ubiquitination		score1	PhosphoSitePlus
	T222	Phosphorylation		score1	PhosphoSitePlus
	S224	Phosphorylation		score1	PhosphoSitePlus
	T225	Phosphorylation		score1	PhosphoSitePlus
	S234	Phosphorylation		score1	PhosphoSitePlus
	S279	Phosphorylation		score2	PhosphoSitePlus UniProt	18691976, 23186163, 24275569, ...19369195

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T51	Phosphorylation		score0	HPRD	18691976
	S205	Phosphorylation		score0	HPRD	18691976
	T225	Phosphorylation		score0	HPRD	20068231
	S279	Phosphorylation		score0	HPRD	18691976

P51948 (MNAT1) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P03372-1 (ESR1)	S102	score1	HPRD	10949034
	P03372-1 (ESR1)	S104	score2	HPRD	8308015, 10949034
	P03372-1 (ESR1)	S106	score2	HPRD	8308015, 10949034
	P03372 (ESR1)	S118	score1	Signor	10949034

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S18	F18	Biomuta		DOID:4159 / skin cancer [ cosmic ]
K180	T180	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]
S205	F205	Biomuta		[ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ]
T225	A225	Biomuta		DOID:3571 / liver cancer [ cosmic ]
S234	L234	Biomuta		DOID:4159 / skin cancer [ cosmic ]
S279	L279	Biomuta		DOID:5158 / pleural cancer [ cosmic ]