iPTMnet Report for P51911 (CNN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51911 / CNN1_HUMAN
Protein Name Calponin-1
Gene Name Name: CNN1
Organism Homo sapiens (Human)

PRO ID PR:P51911
DAG View
PRO Name calponin-1 (human)
Definition A calponin-1 that is encoded in the genome of human.
Short Label hCNN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51911 (CNN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S3 Phosphorylation PhosphoSitePlus
Y12 Phosphorylation PhosphoSitePlus
Y26 Phosphorylation PhosphoSitePlus
T170 Phosphorylation O75116 (ROCK2) neXtProt 10873572
S175 Phosphorylation O75116 (ROCK2) neXtProt   PhosphoSitePlus 10873572
T180 Phosphorylation O75116 (ROCK2) neXtProt   PhosphoSitePlus 10873572
Y182 Phosphorylation PhosphoSitePlus
T184 Phosphorylation O75116 (ROCK2) neXtProt   PhosphoSitePlus 10873572
R185 Methylation PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K225 Acetylation PhosphoSitePlus
T259 Phosphorylation O75116 (ROCK2) neXtProt   PhosphoSitePlus 10873572
Y261 Phosphorylation PhosphoSitePlus
R265 Methylation PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y182 Phosphorylation P06241 (FYN) HPRD 15206927
Y261 Phosphorylation P06241 (FYN) HPRD 15206927


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 C2 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y26 H26 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R185 Q185 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
R185 W185 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T259 M259 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y261 D261 Biomuta DOID:1324 / lung cancer [ cosmic ]
R265 C265 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y294 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]