Protein Information

Cytoscape View


UniProt AC / UniProt ID P51884 / LUM_HUMAN
Protein Name Lumican precursor
Gene Name Name: LUM
Synonyms:LDC,SLRR2D;
Organism Homo sapiens (Human)

PRO ID PR:P51884
DAG View
PRO Name lumican (human)
Definition A lumican that is encoded in the genome of human.
Short Label hLUM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51884 (LUM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K69 Acetylation PhosphoSitePlus
N88 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 14760718, ...29391424, 29741879, 29671580
N127 N-Glycosylation GlyGen 29427759, 32125861, 24190977, ...23090970, 29391424, 29741879, 29671580
S138 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
N160 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 23090970, ...14760718, 29391424, 29741879
S177 Phosphorylation PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
S201 O-Glycosylation GlyGen 23271734, 29351928
S201 Phosphorylation PhosphoSitePlus
T209 O-Glycosylation GlyGen 23271734, 29351928
T209 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
K226 Acetylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
N252 N-Glycosylation GlyGen 29741879
S304 Phosphorylation PhosphoSitePlus
S320 O-Glycosylation GlyGen 30459171
S320 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S138 Y138 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T145 N145 Biomuta DOID:1324 / lung cancer [ tcga ]
S192 N192 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S192 T192 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S201 C201 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
Y233 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y233 N233 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]