iPTMnet Report for P51878 (CASP5)
Protein Information
UniProt AC / UniProt ID | P51878 / CASP5_HUMAN |
Protein Name | Caspase-5 precursor |
Gene Name | Name: CASP5 Synonyms:ICH3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51878 |
PRO Name | caspase-5 (human) |
Definition | A caspase-5 that is encoded in the genome of human. |
Short Label | hCASP5 |
Category | organism-gene |
P51878 (CASP5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y103 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y104 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y228 | Phosphorylation | score1 | PhosphoSitePlus | |||
T229 | Phosphorylation | score1 | PhosphoSitePlus | |||
T237 | Phosphorylation | score1 | PhosphoSitePlus | |||
K282 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S44 | Y44 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
Y103 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y103 | F103 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y228 | C228 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |