Protein Information

Cytoscape View

UniProt AC / UniProt ID P51813 / BMX_HUMAN
Protein Name Cytoplasmic tyrosine-protein kinase BMX
Gene Name Name: BMX
Organism Homo sapiens (Human)

PRO ID PR:P51813
DAG View
PRO Name cytoplasmic tyrosine-protein kinase BMX (human)
Definition A cytoplasmic tyrosine-protein kinase BMX that is encoded in the genome of human.
Short Label hBMX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P51813 (BMX) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y40 Phosphorylation Q05397 (PTK2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 20004564, 11331870, 21408190
T165 Phosphorylation PhosphoSitePlus
K172 Acetylation PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation Q08881 (ITK) , Q06187 (BTK) , P51813 (BMX) , P42680 (TEC) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 12573241
Y224 Phosphorylation Q08881 (ITK) , P42680 (TEC) , P51813 (BMX) , Q06187 (BTK) HPRD   phospho.ELM   Signor   UniProt 12573241
S226 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
K337 Acetylation PhosphoSitePlus
K343 Acetylation PhosphoSitePlus
K347 Acetylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
K395 Acetylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
Y566 Phosphorylation P12931 (SRC) , P51813 (BMX) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 14532277, 10688651
S568 Phosphorylation PhosphoSitePlus

P51813 (BMX) as PTM Enzyme

Substrate Site Score Source PMID
P08581 (MET) Y1235 PhosphoSitePlus 23716717
P11362 (FGFR1) Y653 PhosphoSitePlus 23716717
P11362 (FGFR1) Y654 PhosphoSitePlus 23716717
P51813 (BMX) Y216 UniProt 12573241
P51813 (BMX) Y224 UniProt 12573241
P51813 (BMX) Y566 UniProt 10688651
P56945 (BCAR1) Y12 PhosphoSitePlus 21937722
Q05397 (PTK2) Y194 PhosphoSitePlus 23716717
Q05397 (PTK2) Y441 PhosphoSitePlus 23716717
Q05397 (PTK2) Y576 PhosphoSitePlus 23716717
Q05397 (PTK2) Y577 PhosphoSitePlus   Signor 23716717
Q05397 (PTK2) Y742 PhosphoSitePlus 23716717
Q05397 (PTK2) Y861 PhosphoSitePlus 23716717
Q05397 (PTK2) Y898 PhosphoSitePlus 23716717
Q05397 (PTK2) Y925 PhosphoSitePlus 23716717
Q05397 (PTK2) Y1007 PhosphoSitePlus 23716717
Q07912 (TNK2) Y859 PhosphoSitePlus 23716717
Q07912 (TNK2) Y860 PhosphoSitePlus 23716717
Q16611 (BAK1) Y108 PhosphoSitePlus 25649765
Q96T51 (RUFY1) Y389 neXtProt   phospho.ELM   PhosphoSitePlus 11877430
Q96T51 (RUFY1) Y400 neXtProt   phospho.ELM   PhosphoSitePlus 11877430

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T165 P165 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K181 R181 Biomuta DOID:5041 / esophageal cancer [ icgc ]
Y216 H216 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S226 F226 Biomuta DOID:1612 / breast cancer [ cosmic ]
S324 T324 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S324 L324 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y330 C330 Biomuta DOID:363 / uterine cancer [ tcga ]