iPTMnet Report P51809 VAMP7

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P51809 / VAMP7_HUMAN
Protein Name	Vesicle-associated membrane protein 7
Gene Name	Name: VAMP7 Synonyms:SYBL1;
Organism	Homo sapiens (Human)

PRO ID	PR:P51809 DAG View
PRO Name	vesicle-associated membrane protein 7 (human)
Definition	A vesicle-associated membrane protein 7 that is encoded in the genome of human.
Short Label	hVAMP7
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P51809 (VAMP7) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T12	Phosphorylation		score1	PhosphoSitePlus
	T13	Phosphorylation		score1	PhosphoSitePlus
	Y45	Phosphorylation	P12931 (SRC)	score3	PhosphoSitePlus RLIMS-P	23471971
	K121	Ubiquitination		score1	PhosphoSitePlus
	K125	Ubiquitination		score1	PhosphoSitePlus
	K137	Ubiquitination		score1	PhosphoSitePlus
	K160	Ubiquitination		score1	PhosphoSitePlus
	S167	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
	S168	Phosphorylation		score1	PhosphoSitePlus
	K172	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T12	Phosphorylation		score0	HPRD	19413330
	T13	Phosphorylation		score0	HPRD	19413330
	S167	Phosphorylation		score0	HPRD	20068231
	S168	Phosphorylation		score0	HPRD	19413330, 18767875, 18578522

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y45	C45	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]
S168	C168	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S168	T168	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]