iPTMnet Report for P51798 (CLCN7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51798 / CLCN7_HUMAN
Protein Name H(+)/Cl(-) exchange transporter 7
Gene Name Name: CLCN7
Organism Homo sapiens (Human)

PRO ID PR:P51798
DAG View
PRO Name H(+)/Cl(-) exchange transporter 7 (human)
Definition An H(+)/Cl(-) exchange transporter 7 that is encoded in the genome of human.
Short Label hCLCN7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51798 (CLCN7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S60 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S61 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K93 Sumoylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
C411 Methylation IEDB 31844290
T633 Phosphorylation PhosphoSitePlus
T636 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
S801 Phosphorylation PhosphoSitePlus   UniProt 23186163
T805 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation HPRD 18669648, 20068231
S61 Phosphorylation HPRD 20166139, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 F9 Biomuta DOID:4159 / skin cancer [ cosmic ]
S61 N61 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S61 G61 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K81 N81 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K274 R274 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K274 N274 Biomuta DOID:3571 / liver cancer [ cosmic ]