iPTMnet Report for P51797 (CLCN6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51797 / CLCN6_HUMAN
Protein Name H(+)/Cl(-) exchange transporter 6
Gene Name Name: CLCN6
Synonyms:KIAA0046;
Organism Homo sapiens (Human)

PRO ID PR:P51797
DAG View
PRO Name H(+)/Cl(-) exchange transporter 6 (human)
Definition A chloride channel protein 6 that is encoded in the genome of human.
Short Label hCLCN6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51797 (CLCN6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K46 Ubiquitination PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
N410 N-Glycosylation GlyGen   UniProt 17534424
N422 N-Glycosylation GlyGen   UniProt 17534424
S423 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
N432 N-Glycosylation GlyGen   UniProt 17534424
K648 Methylation PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
Y784 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K658 M658 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K679 N679 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S683 F683 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y784 C784 Biomuta DOID:5041 / esophageal cancer [ cosmic ]