iPTMnet Report for P51795 (CLCN5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51795 / CLCN5_HUMAN
Protein Name H(+)/Cl(-) exchange transporter 5
Gene Name Name: CLCN5
Synonyms:CLCK2;
Organism Homo sapiens (Human)

PRO ID PR:P51795
DAG View
PRO Name H(+)/Cl(-) exchange transporter 5 (human)
Definition An H(+)/Cl(-) exchange transporter 5 that is encoded in the genome of human.
Short Label hCLCN5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51795 (CLCN5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S371 Phosphorylation PhosphoSitePlus
N475 N-Glycosylation GlyGen 24190977
N478 N-Glycosylation GlyGen 24190977
Y495 Phosphorylation PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K57 Ubiquitination PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S58 L58 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K649 M649 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K649 N649 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]