iPTMnet Report for P51784 (USP11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51784 / UBP11_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 11
Gene Name Name: USP11
Synonyms:UHX1;
Organism Homo sapiens (Human)

PRO ID PR:P51784
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 11 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 11 that is encoded in the genome of human.
Short Label hUSP11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51784 (USP11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
Y195 Phosphorylation HPRD   PhosphoSitePlus 20068231
R241 Methylation PhosphoSitePlus
K245 Acetylation PhosphoSitePlus   UniProt 19608861
K245 Ubiquitination PhosphoSitePlus
T268 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
K303 Sumoylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K383 Methylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
C482 Methylation IEDB 31844290
K493 Ubiquitination PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
Y593 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
Y607 Phosphorylation PhosphoSitePlus
Y608 Phosphorylation PhosphoSitePlus
T644 Phosphorylation HPRD 19651622
S648 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 20068231, ...18452278
K664 Ubiquitination PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
T672 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
R677 Methylation PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
T731 Phosphorylation PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus
Y742 Phosphorylation PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
K813 Ubiquitination PhosphoSitePlus
K835 Ubiquitination PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
K896 Ubiquitination PhosphoSitePlus
K920 Ubiquitination PhosphoSitePlus
Y923 Phosphorylation PhosphoSitePlus
S938 Phosphorylation PhosphoSitePlus
S942 Phosphorylation PhosphoSitePlus
S943 Phosphorylation PhosphoSitePlus
S948 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 18669648, 19664995, ...24275569
S952 Phosphorylation PhosphoSitePlus
S953 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
S956 Phosphorylation PhosphoSitePlus
S957 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S31 L31 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
C482 R482 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S606 F606 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S942 L942 Biomuta DOID:4159 / skin cancer [ cosmic ]
S948 P948 Biomuta DOID:10534 / stomach cancer [ cosmic ]