iPTMnet Report P51688 SGSH

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P51688 / SPHM_HUMAN
Protein Name	N-sulphoglucosamine sulphohydrolase precursor
Gene Name	Name: SGSH Synonyms:HSS;
Organism	Homo sapiens (Human)

PRO ID	PR:P51688 DAG View
PRO Name	N-sulphoglucosamine sulphohydrolase (human)
Definition	An N-sulphoglucosamine sulphohydrolase that is encoded in the genome of human.
Short Label	hSGSH
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P51688 (SGSH) as Substrate

P51688

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N41	N-Glycosylation		score4	GlyGen UniProt	29741879, 12754519, 24816101, ...19159218
	Y89	Phosphorylation		score1	PhosphoSitePlus
	K103	Ubiquitination		score1	PhosphoSitePlus
	N151	N-Glycosylation		score3	GlyGen UniProt	24816101
	Y174	Phosphorylation		score1	PhosphoSitePlus
	Y240	Phosphorylation		score1	PhosphoSitePlus
	T241	Phosphorylation		score1	PhosphoSitePlus
	N264	N-Glycosylation		score4	GlyGen UniProt	12754519, 24816101, 24190977
	K303	Ubiquitination		score1	PhosphoSitePlus
	Y330	Phosphorylation		score1	PhosphoSitePlus
	S332	Phosphorylation		score1	PhosphoSitePlus
	T407	Phosphorylation		score1	PhosphoSitePlus
	N413	N-Glycosylation		score4	GlyGen UniProt	24816101, 19159218
	K425	Ubiquitination		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y240	H240	Biomuta		DOID:2531 / hematologic cancer [ cosmic ]
T407	I407	Biomuta		DOID:4159 / skin cancer [ cosmic ]