iPTMnet Report for P51636 (CAV2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51636 / CAV2_HUMAN
Protein Name Caveolin-2
Gene Name Name: CAV2
Organism Homo sapiens (Human)

PRO ID PR:P51636
DAG View
PRO Name caveolin-2 (human)
Definition A caveolin-2 that is encoded in the genome of human.
Short Label hCAV2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51636 (CAV2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
S18 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y19 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20455999, 25753664, 18669648, ...25667086, 12091389, 19427337, 19778377, 15504032
Y19 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12091389, 15504032
S20 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S23 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17081983, 18669648, 18081315, ...12743374
S23 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 12743374
Y27 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15504032, 18669648, 25667086, ...19427337, 12091389
Y27 Phosphorylation P12931 (SRC) neXtProt   Signor 12091389, 15504032
S36 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17081983, 18081315, 12743374
S36 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 12743374
K50 Ubiquitination PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
C122 Methylation IEDB 31844290
S128 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S154 Phosphorylation RLIMS-P 20455999
S156 Phosphorylation RLIMS-P 20455999
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD 18669648, 20068231
Y19 Phosphorylation HPRD 12091389, 18669648, 20068231
Y19 Phosphorylation P12931 (SRC) HPRD 12091389, 18669648, 20068231
S20 Phosphorylation HPRD 20166139, 18669648, 17081983, ...20068231
S23 Phosphorylation HPRD 20166139, 18669648, 12743374
Y27 Phosphorylation HPRD 15504032, 18669648, 20068231
S36 Phosphorylation HPRD 12743374
T121 Phosphorylation HPRD 20068231
S128 Phosphorylation HPRD 20068231
T131 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD 18669648, 20068231
Y19 Phosphorylation HPRD 12091389, 18669648, 20068231
Y19 Phosphorylation P12931 (SRC) HPRD 12091389, 18669648, 20068231
S20 Phosphorylation HPRD 20166139, 18669648, 17081983, ...20068231
S23 Phosphorylation HPRD 20166139, 18669648, 12743374
Y27 Phosphorylation HPRD 15504032, 18669648, 20068231
S36 Phosphorylation HPRD 12743374


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P51636 (CAV2) Y19 P28482 (MAPK1) unknown eFIP 19778377


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y27 S27 Biomuta DOID:4159 / skin cancer [ cosmic, cosmic ]
T121 A121 Biomuta DOID:1319 / brain cancer [ cosmic ]