iPTMnet Report for P51553 (IDH3G)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51553 / IDH3G_HUMAN
Protein Name Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial precursor
Gene Name Name: IDH3G
Organism Homo sapiens (Human)

PRO ID PR:P51553
DAG View
PRO Name isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (human)
Definition An isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial that is encoded in the genome of human.
Short Label hIDH3G
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51553 (IDH3G) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
C81 S-Nitrosylation dbSNO 26338901
K115 Methylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
C148 S-Nitrosylation dbSNO 26338901
K149 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
T170 O-Glycosylation GlyGen 33465208
Y174 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S181 O-Glycosylation GlyGen 33465208
S188 O-Glycosylation GlyGen 33465208
K190 Ubiquitination PhosphoSitePlus
R199 Methylation PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T326 Phosphorylation HPRD 20068231
Y344 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T326 Phosphorylation HPRD 20068231
Y344 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R199 H199 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R199 C199 Biomuta DOID:363 / uterine cancer [ icgc ]
K215 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T326 M326 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y344 F344 Biomuta [ cosmic, cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc, icgc ]