iPTMnet Report for P51512 (MMP16)
Protein Information
UniProt AC / UniProt ID | P51512 / MMP16_HUMAN |
Protein Name | Matrix metalloproteinase-16 precursor |
Gene Name | Name: MMP16 Synonyms:C8orf57; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51512 |
PRO Name | matrix metalloproteinase-16 (human) |
Definition | A matrix metalloproteinase-16 that is encoded in the genome of human. |
Short Label | hMMP16 |
Category | organism-gene |
P51512 (MMP16) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y52 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
S65 | Phosphorylation | score1 | PhosphoSitePlus | |||
T92 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y134 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y377 | Phosphorylation | score1 | PhosphoSitePlus | |||
T382 | Phosphorylation | score1 | PhosphoSitePlus | |||
T478 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y521 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T8 | I8 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y52 | * | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] | |
S61 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S61 | L61 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
T92 | I92 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y134 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y134 | D134 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y134 | F134 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y377 | D377 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] | |
T382 | N382 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
T478 | A478 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T478 | P478 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |