iPTMnet Report for P51511 (MMP15)
Protein Information
UniProt AC / UniProt ID | P51511 / MMP15_HUMAN |
Protein Name | Matrix metalloproteinase-15 precursor |
Gene Name | Name: MMP15 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51511 |
PRO Name | matrix metalloproteinase-15 (human) |
Definition | A matrix metalloproteinase-15 that is encoded in the genome of human. |
Short Label | hMMP15 |
Category | organism-gene |
P51511 (MMP15) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S67 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20058876 | ||
S81 | O-Glycosylation | score1 | GlyGen | 36240223 | ||
T305 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T313 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T318 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T320 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
S551 | Phosphorylation | score1 | PhosphoSitePlus | |||
S589 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 24275569 | ||
Y660 | Phosphorylation | score1 | PhosphoSitePlus | |||
K662 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S81 | L81 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T313 | P313 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] |