Protein Information

Cytoscape View


UniProt AC / UniProt ID P51160 / PDE6C_HUMAN
Protein Name Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' precursor
Gene Name Name: PDE6C
Synonyms:PDEA2;
Organism Homo sapiens (Human)

PRO ID PR:P51160
DAG View
PRO Name cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (human)
Definition A cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' that is encoded in the genome of human.
Short Label hPDE6C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51160 (PDE6C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y266 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
T546 Phosphorylation HPRD   PhosphoSitePlus 18452278
K824 Acetylation PhosphoSitePlus
K831 Acetylation PhosphoSitePlus
K832 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y266 F266 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S469 Y469 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]