iPTMnet Report for P51160 (PDE6C)
Protein Information
| UniProt AC / UniProt ID | P51160 / PDE6C_HUMAN |
| Protein Name | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' precursor |
| Gene Name | Name: PDE6C Synonyms:PDEA2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P51160 |
| PRO Name | cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (human) |
| Definition | A cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' that is encoded in the genome of human. |
| Short Label | hPDE6C |
| Category | organism-gene |
DAG ViewP51160 (PDE6C) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T149 | Phosphorylation | score1 | IEDB | 35494241 | ||
| Y266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T343 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T546 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| K824 | Acetylation | score1 | PhosphoSitePlus | |||
| K831 | Acetylation | score1 | PhosphoSitePlus | |||
| K832 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y266 | F266 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S469 | Y469 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
