iPTMnet Report for P51159 (RAB27A)
Protein Information
| UniProt AC / UniProt ID | P51159 / RB27A_HUMAN |
| Protein Name | Ras-related protein Rab-27A |
| Gene Name | Name: RAB27A Synonyms:RAB27; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P51159 |
| PRO Name | Ras-related protein Rab-27A (human) |
| Definition | A Ras-related protein Rab-27A that is encoded in the genome of human. |
| Short Label | hRAB27A |
| Category | organism-gene |
P51159 (RAB27A) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 22223895, 25944712 | ||
| S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R64 | Methylation | score1 | PhosphoSitePlus | |||
| T75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S211 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y6 | D6 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| R64 | K64 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S192 | F192 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S211 | N211 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
DAG View