iPTMnet Report for P51159 (RAB27A)
Protein Information
UniProt AC / UniProt ID | P51159 / RB27A_HUMAN |
Protein Name | Ras-related protein Rab-27A |
Gene Name | Name: RAB27A Synonyms:RAB27; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51159 |
PRO Name | Ras-related protein Rab-27A (human) |
Definition | A Ras-related protein Rab-27A that is encoded in the genome of human. |
Short Label | hRAB27A |
Category | organism-gene |
P51159 (RAB27A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22223895, 25944712 | ||
S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y6 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y27 | Phosphorylation | score1 | PhosphoSitePlus | |||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
R64 | Methylation | score1 | PhosphoSitePlus | |||
T75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
S211 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y6 | D6 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
R64 | K64 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S192 | F192 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S211 | N211 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |