iPTMnet Report for P51148 (RAB5C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51148 / RAB5C_HUMAN
Protein Name Ras-related protein Rab-5C
Gene Name Name: RAB5C
Synonyms:RABL;
Organism Homo sapiens (Human)

PRO ID PR:P51148
DAG View
PRO Name Ras-related protein Rab-5C (human)
Definition A Ras-related protein Rab-5C that is encoded in the genome of human.
Short Label hRAB5C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51148 (RAB5C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
R9 Methylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus   UniProt 29125462
K117 Ubiquitination PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S209 O-Glycosylation GlyGen 23301498, 34019948, 34725712, ...35083852, 31373491
S209 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R4 W4 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
R4 Q4 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R9 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R9 Q9 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S30 F30 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K117 R117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K135 T135 Biomuta DOID:1319 / brain cancer [ icgc ]
K180 N180 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]