iPTMnet Report for P50851 (LRBA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50851 / LRBA_HUMAN
Protein Name Lipopolysaccharide-responsive and beige-like anchor protein
Gene Name Name: LRBA
Synonyms:BGL;
Organism Homo sapiens (Human)

PRO ID PR:P50851
DAG View
PRO Name lipopolysaccharide-responsive and beige-like anchor protein (human)
Definition A lipopolysaccharide-responsive and beige-like anchor protein that is encoded in the genome of human.
Short Label hLRBA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50851 (LRBA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692
S3 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
T14 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K393 Acetylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
Y409 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
K731 Ubiquitination PhosphoSitePlus
Y745 Phosphorylation PhosphoSitePlus
K820 Ubiquitination PhosphoSitePlus
T824 Phosphorylation PhosphoSitePlus
N851 N-Glycosylation GlyGen 23090970
S968 Phosphorylation PhosphoSitePlus
S971 Phosphorylation PhosphoSitePlus
T976 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S979 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T987 Phosphorylation PhosphoSitePlus
S1005 Phosphorylation PhosphoSitePlus
T1011 Phosphorylation PhosphoSitePlus
Y1016 Phosphorylation PhosphoSitePlus
T1033 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1064 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
S1100 Phosphorylation PhosphoSitePlus   UniProt 21406692
Y1110 Phosphorylation PhosphoSitePlus
S1118 Phosphorylation PhosphoSitePlus
T1120 Phosphorylation PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1139 Phosphorylation PhosphoSitePlus   UniProt 21406692
K1160 Ubiquitination PhosphoSitePlus
T1167 Phosphorylation PhosphoSitePlus
T1171 Phosphorylation PhosphoSitePlus
S1188 Phosphorylation PhosphoSitePlus
S1191 Phosphorylation PhosphoSitePlus
T1194 Phosphorylation PhosphoSitePlus
T1222 Phosphorylation PhosphoSitePlus
S1231 Phosphorylation PhosphoSitePlus
S1233 O-Glycosylation GlyGen 23301498, 32119511, 35132862, ...28510447, 29351928
S1233 Phosphorylation PhosphoSitePlus
S1236 Phosphorylation PhosphoSitePlus
K1243 Ubiquitination PhosphoSitePlus
S1247 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1251 Phosphorylation PhosphoSitePlus
K1259 Ubiquitination PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S1299 Phosphorylation PhosphoSitePlus
C1458 Methylation IEDB 31844290
K1465 Ubiquitination PhosphoSitePlus
K1473 Ubiquitination PhosphoSitePlus
S1477 Phosphorylation PhosphoSitePlus
K1483 Ubiquitination PhosphoSitePlus
S1484 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1487 Ubiquitination PhosphoSitePlus
S1488 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T1494 Phosphorylation PhosphoSitePlus
S1498 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1568 Phosphorylation PhosphoSitePlus
S1605 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1611 Phosphorylation PhosphoSitePlus
T1613 Phosphorylation PhosphoSitePlus
T1654 Phosphorylation PhosphoSitePlus
K1665 Ubiquitination PhosphoSitePlus
T1667 Phosphorylation PhosphoSitePlus
K1674 Ubiquitination PhosphoSitePlus
K1679 Ubiquitination PhosphoSitePlus
S1721 Phosphorylation PhosphoSitePlus
S1725 Phosphorylation PhosphoSitePlus
S1736 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1738 Phosphorylation PhosphoSitePlus
S1743 Phosphorylation phospho.ELM 18669648
S1757 Phosphorylation PhosphoSitePlus
S1767 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1770 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1776 Ubiquitination PhosphoSitePlus
T1782 Phosphorylation PhosphoSitePlus
S1785 Phosphorylation PhosphoSitePlus
S1787 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K1806 Ubiquitination PhosphoSitePlus
K1889 Ubiquitination PhosphoSitePlus
S1904 Phosphorylation PhosphoSitePlus
K1928 Ubiquitination PhosphoSitePlus
C1935 Methylation IEDB 31844290
T2028 Phosphorylation PhosphoSitePlus
S2039 Phosphorylation PhosphoSitePlus
S2050 Phosphorylation PhosphoSitePlus
T2062 Phosphorylation PhosphoSitePlus
S2064 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2065 Phosphorylation PhosphoSitePlus
K2116 Acetylation PhosphoSitePlus
K2117 Acetylation PhosphoSitePlus
Y2146 Phosphorylation PhosphoSitePlus
S2198 Phosphorylation PhosphoSitePlus
S2201 Phosphorylation PhosphoSitePlus
K2207 Ubiquitination PhosphoSitePlus
S2270 Phosphorylation PhosphoSitePlus
K2271 Ubiquitination PhosphoSitePlus
K2279 Ubiquitination PhosphoSitePlus
R2338 Methylation PhosphoSitePlus
S2496 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2518 O-Glycosylation GlyGen 23301498, 32119511, 35132862, ...28510447, 29351928
T2540 O-Glycosylation GlyGen 23301498, 32119511, 35132862, ...28510447, 29351928
C2643 Methylation IEDB 31844290
C2655 Methylation IEDB 31844290
K2742 Ubiquitination PhosphoSitePlus
K2744 Acetylation IEDB 34357683
K2744 Ubiquitination PhosphoSitePlus
C2754 Methylation IEDB 31844290
Y2849 Phosphorylation PhosphoSitePlus
Y2859 Phosphorylation PhosphoSitePlus
T2861 Phosphorylation PhosphoSitePlus
Y2863 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 19664994, 17081983
T14 Phosphorylation HPRD 17081983
S34 Phosphorylation HPRD 17081983
T620 Phosphorylation HPRD 20068231
T976 Phosphorylation HPRD 18669648
S979 Phosphorylation HPRD 18669648
Y1016 Phosphorylation HPRD 19413330
S1051 Phosphorylation HPRD 20068231
T1067 Phosphorylation HPRD 20068231
S1100 Phosphorylation HPRD 19651622, 19664994
S1118 Phosphorylation HPRD 19413330, 20068231
T1120 Phosphorylation HPRD 19413330
S1133 Phosphorylation HPRD 20068231
S1135 Phosphorylation HPRD 19413330, 20068231
S1261 Phosphorylation HPRD 20068231
S1484 Phosphorylation HPRD 18669648
S1488 Phosphorylation HPRD 18669648, 20068231
T1667 Phosphorylation HPRD 19007248
S1736 Phosphorylation HPRD 18669648
S1743 Phosphorylation HPRD 18669648
S1767 Phosphorylation HPRD 18669648
S1770 Phosphorylation HPRD 18669648
S1787 Phosphorylation HPRD 17525332
S1885 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K2024 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K405 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y409 * Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S541 R541 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y745 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S979 C979 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T1011 A1011 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1064 F1064 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1086 L1086 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1135 C1135 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1139 P1139 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1243 N1243 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T1251 A1251 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1473 Q1473 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1477 N1477 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1487 N1487 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1667 A1667 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K1679 E1679 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1721 Y1721 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1736 L1736 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1767 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1885 R1885 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1885 N1885 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1904 N1904 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K2117 N2117 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S2198 L2198 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R2338 Q2338 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R2338 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]