iPTMnet Report for P50749 (RASSF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50749 / RASF2_HUMAN
Protein Name Ras association domain-containing protein 2
Gene Name Name: RASSF2
Synonyms:CENP-34;
Organism Homo sapiens (Human)

PRO ID PR:P50749
DAG View
PRO Name Ras association domain-containing protein 2 (human)
Definition A Ras association domain-containing protein 2 that is encoded in the genome of human.
Short Label hRASSF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50749 (RASSF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
R142 Methylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
R144 Methylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
R151 Methylation PhosphoSitePlus
R165 Methylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
Y270 Phosphorylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S145 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 P8 Biomuta DOID:363 / uterine cancer [ icgc ]
R142 C142 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R142 H142 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ cosmic ]
R144 C144 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R144 H144 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
R151 H151 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
R151 C151 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
R165 T165 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K211 T211 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]