iPTMnet Report for P50748 (KNTC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50748 / KNTC1_HUMAN
Protein Name Kinetochore-associated protein 1
Gene Name Name: KNTC1
Synonyms:KIAA0166;
Organism Homo sapiens (Human)

PRO ID PR:P50748
DAG View
PRO Name kinetochore-associated protein 1 (human)
Definition A kinetochore-associated protein 1 that is encoded in the genome of human.
Short Label hKNTC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50748 (KNTC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
C372 Methylation IEDB 31844290
K377 Ubiquitination PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
K437 Ubiquitination PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
K726 Acetylation PhosphoSitePlus
K726 Ubiquitination PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
K829 Ubiquitination PhosphoSitePlus
K831 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
Y849 Phosphorylation PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
Y867 Phosphorylation PhosphoSitePlus
K870 Ubiquitination PhosphoSitePlus
K916 Ubiquitination PhosphoSitePlus
K957 Ubiquitination PhosphoSitePlus
K971 Ubiquitination PhosphoSitePlus
K976 Ubiquitination PhosphoSitePlus
K985 Ubiquitination PhosphoSitePlus
K1021 Ubiquitination PhosphoSitePlus
K1031 Ubiquitination PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
T1035 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 23186163
S1045 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 23186163
K1051 Ubiquitination PhosphoSitePlus
T1071 Phosphorylation PhosphoSitePlus
K1076 Acetylation PhosphoSitePlus
K1076 Ubiquitination PhosphoSitePlus
K1081 Acetylation PhosphoSitePlus
K1081 Ubiquitination PhosphoSitePlus
K1085 Acetylation PhosphoSitePlus
K1086 Ubiquitination PhosphoSitePlus
K1307 Ubiquitination PhosphoSitePlus
S1379 Phosphorylation PhosphoSitePlus
Y1389 Phosphorylation PhosphoSitePlus
K1413 Ubiquitination PhosphoSitePlus
T1428 Phosphorylation PhosphoSitePlus
K1497 Ubiquitination PhosphoSitePlus
K1543 Ubiquitination PhosphoSitePlus
K1557 Ubiquitination PhosphoSitePlus
S1624 Phosphorylation IEDB 32387766
S1630 Phosphorylation PhosphoSitePlus
T1633 Phosphorylation PhosphoSitePlus
Y1635 Phosphorylation PhosphoSitePlus
K1653 Ubiquitination PhosphoSitePlus
T1655 Phosphorylation PhosphoSitePlus
K1658 Ubiquitination PhosphoSitePlus
S1660 Phosphorylation PhosphoSitePlus
T1661 Phosphorylation PhosphoSitePlus
K1665 Ubiquitination PhosphoSitePlus
K1731 Ubiquitination PhosphoSitePlus
K1738 Ubiquitination PhosphoSitePlus
Y1762 Phosphorylation PhosphoSitePlus
K1802 Ubiquitination PhosphoSitePlus
S1904 Phosphorylation IEDB 35494241
C1919 Methylation IEDB 31844290
S1955 Phosphorylation PhosphoSitePlus
Y1974 Phosphorylation PhosphoSitePlus
Y1994 Phosphorylation PhosphoSitePlus
K2093 Ubiquitination PhosphoSitePlus
S2098 Phosphorylation PhosphoSitePlus
K2136 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S535 Phosphorylation HPRD 18452278
S1034 Phosphorylation HPRD 20068231
T1545 Phosphorylation HPRD 20068231
Y1994 Phosphorylation HPRD 20068231
S2098 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S769 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S769 T769 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K971 E971 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1045 G1045 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
Y1389 C1389 Biomuta DOID:363 / uterine cancer [ cosmic ]
T1428 A1428 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1624 L1624 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S1624 W1624 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1660 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K1802 Q1802 Biomuta DOID:4159 / skin cancer [ cosmic ]
K2093 N2093 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2098 F2098 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]