iPTMnet Report for P50616 (TOB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50616 / TOB1_HUMAN
Protein Name Protein Tob1
Gene Name Name: TOB1
Synonyms:TOB,TROB1;
Organism Homo sapiens (Human)

PRO ID PR:P50616
DAG View
PRO Name protein Tob1 (human)
Definition A protein Tob1 that is encoded in the genome of human.
Short Label hTOB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50616 (TOB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y40 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S152 Phosphorylation P45984 (MAPK9) , P28482 (MAPK1) , P27361 (MAPK3) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 12151396, 12050114
S154 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) , P45984 (MAPK9) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20068231, 12151396, 12050114
S164 Phosphorylation P45984 (MAPK9) , P28482 (MAPK1) , P27361 (MAPK3) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20068231, 12151396, 12050114
T204 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19690332, 20068231
S205 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S268 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 R73 Biomuta DOID:263 / kidney cancer [ cosmic ]
S164 N164 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S205 F205 Biomuta DOID:11054 / urinary bladder cancer [ icgc, tcga ]