iPTMnet Report for P50616 (TOB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50616 / TOB1_HUMAN
Protein Name Protein Tob1
Gene Name Name: TOB1
Synonyms:TOB,TROB1;
Organism Homo sapiens (Human)

PRO ID PR:P50616
DAG View
PRO Name protein Tob1 (human)
Definition A protein Tob1 that is encoded in the genome of human.
Short Label hTOB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50616 (TOB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y40 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S152 Phosphorylation P45984 (MAPK9) , P27361 (MAPK3) , P28482 (MAPK1) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 12151396, 12050114
S154 Phosphorylation P45984 (MAPK9) , P27361 (MAPK3) , P28482 (MAPK1) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20068231, 12151396, 12050114
S164 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) , P45984 (MAPK9) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20068231, 12151396, 12050114
S171 O-Glycosylation GlyGen 28657654, 35254053
T172 O-Glycosylation GlyGen 28657654, 35254053
T172 Phosphorylation PhosphoSitePlus   RLIMS-P 31497236
T204 Phosphorylation HPRD   IEDB   PhosphoSitePlus   UniProt 32387766, 19690332, 20068231
S205 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus 18669648, 32387766
S225 Phosphorylation IEDB 32357974
S268 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus   RLIMS-P 31497236


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 R73 Biomuta DOID:263 / kidney cancer [ cosmic ]
S171 F171 Biomuta DOID:4159 / skin cancer [ cosmic ]
S205 F205 Biomuta [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]