Protein Information

Cytoscape View


UniProt AC / UniProt ID P50583 / AP4A_HUMAN
Protein Name Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Gene Name Name: NUDT2
Synonyms:APAH1;
Organism Homo sapiens (Human)

PRO ID PR:P50583
DAG View
PRO Name bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (human)
Definition A bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] that is encoded in the genome of human.
Short Label hNUDT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50583 (NUDT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K42 E42 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y114 S114 Biomuta DOID:9256 / colorectal cancer [ cosmic ]