iPTMnet Report for P50583 (NUDT2)
Protein Information
| UniProt AC / UniProt ID | P50583 / AP4A_HUMAN |
| Protein Name | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] |
| Gene Name | Name: NUDT2 Synonyms:APAH1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P50583 |
| PRO Name | bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (human) |
| Definition | A bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] that is encoded in the genome of human. |
| Short Label | hNUDT2 |
| Category | organism-gene |
P50583 (NUDT2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K77 | Acetylation | score1 | PhosphoSitePlus | |||
| Y114 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K42 | E42 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y114 | S114 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View