Protein Information

Cytoscape View

UniProt AC / UniProt ID P50548 / ERF_HUMAN
Protein Name ETS domain-containing transcription factor ERF
Gene Name Name: ERF
Organism Homo sapiens (Human)

PRO ID PR:P50548
DAG View
PRO Name ETS domain-containing transcription factor ERF (human)
Definition An ETS domain-containing transcription factor ERF that is encoded in the genome of human.
Short Label hERF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P50548 (ERF) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
K2 Ubiquitination PhosphoSitePlus
T3 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T7 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y16 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K17 Ubiquitination PhosphoSitePlus
S20 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S21 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S24 Phosphorylation PhosphoSitePlus   UniProt 23186163
K71 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S147 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T148 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S150 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S154 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T156 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S161 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10330152, 18669648
S166 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S171 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
R183 Methylation PhosphoSitePlus
S185 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S187 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S190 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
R218 Methylation PhosphoSitePlus
R224 Methylation PhosphoSitePlus
R233 Methylation PhosphoSitePlus
S246 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10330152, 14729966
S251 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10330152, 14729966
S327 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
R329 Methylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
K376 Methylation PhosphoSitePlus
K378 Sumoylation PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
S431 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S435 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T441 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S444 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T456 Phosphorylation PhosphoSitePlus
K465 Sumoylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
K512 Sumoylation PhosphoSitePlus
T526 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 14729966, 22028470, 23186163, ...16964243, 7588608, 10330152, 18669648, 24275569, 19690332
S531 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S532 Phosphorylation PhosphoSitePlus   UniProt 23186163
S542 Phosphorylation PhosphoSitePlus
S548 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation HPRD 18669648
T7 Phosphorylation HPRD 18669648
Y16 Phosphorylation HPRD 18669648
S20 Phosphorylation HPRD 18669648
S21 Phosphorylation HPRD 18669648, 17081983, 18707149
S147 Phosphorylation HPRD 18669648
T148 Phosphorylation HPRD 18669648
S150 Phosphorylation HPRD 18669648
S154 Phosphorylation HPRD 18669648
T156 Phosphorylation HPRD 18669648
S161 Phosphorylation P28482 (MAPK1) HPRD 10330152, 18669648
S171 Phosphorylation HPRD 18669648
S185 Phosphorylation HPRD 18669648, 17081983
S187 Phosphorylation HPRD 18669648, 17081983
S190 Phosphorylation HPRD 18669648, 17081983
S246 Phosphorylation P28482 (MAPK1) HPRD 10330152
S251 Phosphorylation P28482 (MAPK1) HPRD 10330152
S327 Phosphorylation HPRD 18669648
S431 Phosphorylation HPRD 18669648
S435 Phosphorylation HPRD 18669648
T441 Phosphorylation HPRD 18669648
S444 Phosphorylation HPRD 18669648
S489 Phosphorylation HPRD 18212344
T526 Phosphorylation P28482 (MAPK1) HPRD 10330152, 18669648, 19664994, ...18212344
S531 Phosphorylation HPRD 18767875, 18669648, 17081983
S548 Phosphorylation HPRD 18669648


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047326 (hERF/Phos:1) pT526 PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K2 E2 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S20 L20 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S24 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
S131 G131 Biomuta DOID:3571 / liver cancer [ tcga ]
T148 M148 Biomuta DOID:10534 / stomach cancer [ tcga ]
R329 H329 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ]
R329 C329 Biomuta DOID:1324 / lung cancer [ cosmic ]
R329 S329 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T357 N357 Biomuta DOID:263 / kidney cancer [ cosmic ]
S367 F367 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S368 F368 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S542 A542 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]