iPTMnet Report for P50479 (PDLIM4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50479 / PDLI4_HUMAN
Protein Name PDZ and LIM domain protein 4
Gene Name Name: PDLIM4
Synonyms:RIL;
Organism Homo sapiens (Human)

PRO ID PR:P50479
DAG View
PRO Name PDZ and LIM domain protein 4 (human)
Definition A PDZ and LIM domain protein 4 that is encoded in the genome of human.
Short Label hPDLIM4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50479 (PDLIM4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R8 Methylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
R21 Methylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 24275569
T114 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S120 Phosphorylation neXtProt   PhosphoSitePlus 21644927
T122 Phosphorylation PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
Y191 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
T265 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S112 Phosphorylation HPRD 19651622, 20166139, 19664995, ...20230923
T114 Phosphorylation HPRD 19651622, 20230923
T115 Phosphorylation HPRD 20230923
S116 Phosphorylation HPRD 20230923


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 L11 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T114 K114 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S116 C116 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S116 I116 Biomuta DOID:3571 / liver cancer [ cosmic ]
S188 F188 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S188 P188 Biomuta DOID:10283 / prostate cancer [ cosmic ]