iPTMnet Report for P50454 (SERPINH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50454 / SERPH_HUMAN
Protein Name Serpin H1 precursor
Gene Name Name: SERPINH1
Synonyms:CBP1,CBP2,HSP47,SERPINH2;ORFNames:PIG14;
Organism Homo sapiens (Human)

PRO ID PR:P50454
DAG View
PRO Name serpin H1 (human)
Definition A serpin H1 that is encoded in the genome of human.
Short Label hSERPINH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50454 (SERPINH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
T32 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S47 O-Glycosylation GlyGen 31373491
S47 Phosphorylation HPRD   PhosphoSitePlus 20068231
S53 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...22661428, 34725712, 30444036, 31373491, 34019948, 35083852, 34229054
Y55 Phosphorylation HPRD 20068231
S70 O-Glycosylation GlyGen 31373491
S70 Phosphorylation PhosphoSitePlus
S76 O-Glycosylation GlyGen 31373491
S76 Phosphorylation HPRD 20068231
S77 Phosphorylation HPRD 20068231
K94 Ubiquitination PhosphoSitePlus
S98 Phosphorylation HPRD   PhosphoSitePlus 20068231
N120 N-Glycosylation GlyGen 23090970, 29741879, 23345538, ...24190977
N125 N-Glycosylation GlyGen 29741879, 23345538
K129 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus   UniProt 23186163
S149 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
T240 Phosphorylation HPRD 20068231
Y243 Phosphorylation HPRD 20068231
Y245 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
K250 Sumoylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K263 Methylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N120 N-Glycosylation PRO 29741879, 23345538
N125 N-Glycosylation PRO 23345538


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S76 L76 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S77 L77 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S141 I141 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K151 R151 Biomuta DOID:3571 / liver cancer [ cosmic ]
S159 C159 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K252 N252 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K291 N291 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K308 E308 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S399 F399 Biomuta DOID:4159 / skin cancer [ cosmic ]